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Bus from Philadelphia to Durham

Book your bus ticket to Durham from Philadelphia today

Duration 10 hours 25 minutes (fastest time)

Departures Up to 2 services per day

Why travel with megabus?

Power outlets onboard*

Express service

Green certified

* Subject to availability

Philadelphia to Durham bus details

Our route M21 bus stops at 6 stops between Philadelphia and Durham. The bus sets off from Northeast Corner of Schuylkill Ave and Walnut Street and drops you off at Durham Transportation Center - Bus Bay T


The Megabus stop in Philadelphia has relocated to the Northeast Corner of the intersection of Schuylkill Ave and Walnut Street. The location is about 2 blocks south of the 30th Street Train Station.

The 30th Street location is no longer in use.

There is an additional stop for the New York service only, located on the south side of Market Street, just west of the intersection of Market Street and North 6th Street. This stop is unaffected by the changes.

Plan your bus trip to Philadelphia


The Megabus stop for all Durham arrivals and departures is located at the Durham Transportation Center, located at 515 West Pettigrew Street, Durham, NC. Waiting room facilities are open 6:00 am until midnight, daily. Drop off and pickup areas are available on W. Pettigrew St. near the taxi zone. No customer vehicles are allowed in bus bay section of the facility and violators will be subject to citation.
Bus from Philadelphia to Durham with megabus

Our Buses

We are very proud of our fleet of state of the art buses.

* Subject to availability

Frequently Asked Questions

How long does it take to travel from Philadelphia to Durham by bus?

The fastest bus from Philadelphia to Durham takes 10 hours 25 minutes

When is the first bus from Philadelphia to Durham?

The earliest bus from Philadelphia to Durham leaves at 1:25 AM

When is the last bus from Philadelphia to Durham?

The latest bus from Philadelphia to Durham leaves at 2:55 AM

How many daily bus trips are there from Philadelphia to Durham?

Megabus runs up to 2 trips per day from Philadelphia to Durham