Bus from Des Moines to Indianapolis
Book your bus ticket to Indianapolis from Des Moines today
Duration 9 hours 30 minutes (fastest time)
Departures Up to 1 service per day
Why travel with megabus?
Power outlets onboard*
Express service
Green certified
* Subject to availability
Des Moines to Indianapolis bus details
Our route BT05 bus stops at 12 stops between Des Moines and Indianapolis. The bus sets off from Burlington Trailways Bus Stop at Des Moines - 1641 E. Euclid and drops you off at Miller Transportation / Burlington Trailways Bus Stop at Indianapolis - 350 South Illinois Street
Des Moines
Indianapolis
Our Buses
We are very proud of our fleet of state of the art buses.
- Individual power outlets*
- Reclining seats
- Reserved seating
- Onboard Restrooms
- Travel in luxury with megabus
* Subject to availability
Frequently Asked Questions
How long does it take to travel from Des Moines to Indianapolis by bus?
The fastest bus from Des Moines to Indianapolis takes 9 hours 30 minutes
When is the first bus from Des Moines to Indianapolis?
The earliest bus from Des Moines to Indianapolis leaves at 8:15 AM
When is the last bus from Des Moines to Indianapolis?
The latest bus from Des Moines to Indianapolis leaves at 8:15 AM
How many daily bus trips are there from Des Moines to Indianapolis?
megabus runs up to 1 trips per day from Des Moines to Indianapolis. View our departure schedule and book your trip
How can I pay for my Des Moines to Indianapolis bus ticket?
megabus offers a wide range of payment methods for our tickets, including major credit card providers and Google pay.
Where is the Des Moines megabus bus stop?
The bus sets off from Burlington Trailways Bus Stop at Des Moines - 1641 E. Euclid
Where is the Indianapolis megabus bus stop?
The bus drops you off at Miller Transportation / Burlington Trailways Bus Stop at Indianapolis - 350 South Illinois Street
Can I track my Des Moines to Indianapolis bus ?
megabus offers real-time bus tracking on our website, so you check your bus location by service number or route. No getting caught off guard with delays here!
How much does it cost to take the bus from Des Moines to Indianapolis?
Traveling with megabus is one of the most affordable options, with tickets starting at just $1*
* Plus a reservation fee and based on availability on megabus operated routes only.