You are using an outdated browser. Please upgrade your browser to improve your experience and security.

Bus from Chicago to Des Moines

Book your bus ticket to Des Moines from Chicago today

Duration 7 hours 10 minutes (fastest time)

Departures Up to 2 services per day

Why travel with Megabus?

Multiple Stops, One Transaction

Real Time Bus Tracking

Award Winning Customer Service

Chicago to Des Moines bus details

Our route BT06 bus stops at 6 stops between Chicago and Des Moines. The bus sets off from Burlington Trailways Bus Stop at Chicago - 630 West Harrison St. and drops you off at Burlington Trailways Bus Stop at Des Moines - 1641 E. Euclid

Chicago

Des Moines

Bus from Chicago to Des Moines with megabus

Our Network

We serve 500+ North American cities through partner operated routes. When you buy bus tickets with Megabus, we offer options to take you from your point of origin to your final destination in one transaction across multiple partners (if needed).

Frequently Asked Questions

How long does it take to travel from Chicago to Des Moines by bus?

The fastest bus from Chicago to Des Moines takes 7 hours 10 minutes

When is the first bus from Chicago to Des Moines?

The earliest bus from Chicago to Des Moines leaves at 11:00 AM

When is the last bus from Chicago to Des Moines?

The latest bus from Chicago to Des Moines leaves at 4:00 PM

How many daily bus trips are there from Chicago to Des Moines?

megabus runs up to 2 trips per day from Chicago to Des Moines. View our departure schedule and book your trip

How can I pay for my Chicago to Des Moines bus ticket?

megabus offers a wide range of payment methods for our tickets, including major credit card providers and Google pay.

Where is the Chicago megabus bus stop?

The bus sets off from Burlington Trailways Bus Stop at Chicago - 630 West Harrison St.

Where is the Des Moines megabus bus stop?

The bus drops you off at Burlington Trailways Bus Stop at Des Moines - 1641 E. Euclid

Can I track my Chicago to Des Moines bus ?

megabus offers real-time bus tracking on our website, so you check your bus location by service number or route. No getting caught off guard with delays here!