Bus from Louisville to Chicago
Book your bus ticket to Chicago from Louisville today
Duration 6 hours 05 minutes (fastest time)
Departures Up to 2 services per day
Why travel with megabus?
Power outlets onboard*
Megabus RIDE onboard entertainment*
* Subject to availability
Louisville to Chicago bus details
Our route M9 bus stops at 3 stops between Louisville and Chicago. The bus sets off from W Muhammad Ali Blvd at the Northwest Corner of of S. 7th Street and drops you off at Megabus stop on W Polk St. between S Clinton St and S Canal St
The bus stop in Louisville is located at 701 W. Muhammad Ali Blvd., at the northwest corner of S. 7th St.
Please check your reservation for the correct location of your bus stop in Chicago!
All megabus.com and Windstar Lines operated arrivals AND departures are located at W Polk St. between S Clinton St and S Canal St.
Van Galder operated trips to/from Madison, WI will remain at their regular stop on S. Canal Street.
Plan your bus trip to Chicago
Frequently Asked Questions
How long does it take to travel from Louisville to Chicago by bus?
The fastest bus from Louisville to Chicago takes 6 hours 05 minutes
When is the first bus from Louisville to Chicago?
The earliest bus from Louisville to Chicago leaves at 3:15 PM
When is the last bus from Louisville to Chicago?
The latest bus from Louisville to Chicago leaves at 11:45 PM
How many daily bus trips are there from Louisville to Chicago?
Megabus runs up to 2 trips per day from Louisville to Chicago