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St. Louis to Chicago Bus & Chicago to St. Louis Bus


Traveling St. Louis to Chicago or Chicago to St. Louis? Get the best bus travel in the Midwest with megabus.com! Catch a ride on one of our spacious signature double decker buses on a bus to St. Louis or a bus to Chicago. The absolute best buses available, starting from just $1 and a reservation fee! Because we value your comfort and convenience, all of our passengers are provided with Wi-Fi and power outlets free of charge! With many arrival times every day to each of these two great American cities, feel free to plan your trip accordingly - you don't work around us, we work around you! See why millions of travelers across North America have trusted their trips with us and keep coming back for the low cost and convenience megabus.com uniquely provides. Our buses to St. Louis arrive at Bay 10 of the Gateway Multi-Modal Transportation Center at 430 South 15th Street. On the Chicago end of this line, megabus.com will arrive and depart from Van Buren Street between South Canal and Clinton Street. Book online today for a St. Louis to Chicago or a Chicago to St. Louis bus. Let's get on the road!


Bus to Chicago

Book your travel with megabus.com for the best Chicago bus! Whether you're headed back to school, visiting friends or family, going on a business trip, trying to get to a sporting event, taking a vacation (or a mix of any of these) - megabus.com is there to get you from St. Louis to Chicago hassle free! Upon arrival we recommend seeing some of what the great city of Chicago has to offer with famous attractions like Navy Pier, Millennium Park, food tours and architecture cruises, the Willis Tower Sky Deck and more! Chicago is one of world's hottest tourist destinations, the Midwest's hub for business, and with megabus.com service we promise the best travel to Chicago available - fast, safe, and with all the leg room and amenities you could desire! In Chicago, transfers are simple too! Many riders use us as a means to get all over the country from our vast Chicago transportation network. Your low cost Chicago bus can get you as far as Atlanta, Texas, Tennessee, The University of Wisconsin at Madison, the University of Michigan at Ann Arbor, New York City, Omaha, NE or just a quick trip over from Chicago to Detroit if you so desire. There's just so many places to go! Book today online for your St. Louis to Chicago bus trip and see the possibilities with megabus.com!

St Louis

Bus to St. Louis

Take a megabus.com bus to St. Louis from Chicago! Whatever your travel needs are, let us be the ones to get you there! While you're in town, we reccomend seeing the Gateway Arch, getting fired up at a Rams, Cardinals, or Blues game, checking out Six Flags St. Louis for a day full of fun, enjoying the nightlife and music scene (or the wildlife scene at the famous St. Louis Zoo), feasting on some amazing local grub, visiting the many wonderful museums, and that's just the beginning! Those are just a few pieces of the adventure that awaits with a bus to St. Louis from megabus.com! We promise easy bus service from Chicago to St. Louis so you can enjoy your trip to fullest and not worry for a second about your travel! Book today, with megabus.com buses to St. Louis starting from just $1 as always.

Catch a ride with us on one of our buses to St. Louis or buses to Chicago! Megabus.com is your fast, safe, and convenient travel partner for any trip in the midwest. We get you from city center to city center at a low cost and with many arrival times to choose from every day. Take our bus to Chicago from St. Louis or St. Louis from Chicago and see why this route is one of the most popular among our riders! Book today and get where you need to go for as low as just a buck!